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In vitro and in vivo MMP gene expression localisation by In Situ-RT-PCR in cell culture and paraffin embedded human breast cancer cell line xenografts

BACKGROUND: Members of the matrix metalloproteinase (MMP) family of proteases are required for the degradation of the basement membrane and extracellular matrix in both normal and pathological conditions. In vitro, MT1-MMP (MMP-14, membrane type-1-MMP) expression is higher in more invasive human bre...

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Detalles Bibliográficos
Autores principales: Haupt, Larisa M, Thompson, Erik W, Trezise, Ann EO, Irving, Rachel E, Irving, Michael G, Griffiths, Lyn R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1397851/
https://www.ncbi.nlm.nih.gov/pubmed/16430785
http://dx.doi.org/10.1186/1471-2407-6-18