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In vitro and in vivo MMP gene expression localisation by In Situ-RT-PCR in cell culture and paraffin embedded human breast cancer cell line xenografts
BACKGROUND: Members of the matrix metalloproteinase (MMP) family of proteases are required for the degradation of the basement membrane and extracellular matrix in both normal and pathological conditions. In vitro, MT1-MMP (MMP-14, membrane type-1-MMP) expression is higher in more invasive human bre...
Autores principales: | Haupt, Larisa M, Thompson, Erik W, Trezise, Ann EO, Irving, Rachel E, Irving, Michael G, Griffiths, Lyn R |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1397851/ https://www.ncbi.nlm.nih.gov/pubmed/16430785 http://dx.doi.org/10.1186/1471-2407-6-18 |
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