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Synthesis and glycosidase inhibitory activity of new hexa-substituted C8-glycomimetics

BACKGROUND: Glycosidases are involved in several metabolic pathways and the development of inhibitors is an important challenge towards the treatment of diseases, such as diabetes, cancer and viral infections including AIDS. Thus, inhibition of intestinal α-glucosidases can be used to treat diabetes...

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Detalles Bibliográficos
Autores principales: Andriuzzi, Olivia, Gravier-Pelletier, Christine, Bertho, Gildas, Prangé, Thierry, Le Merrer, Yves
Formato: Texto
Lenguaje:English
Publicado: Beilstein-Institut 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1399460/
https://www.ncbi.nlm.nih.gov/pubmed/16542023
http://dx.doi.org/10.1186/1860-5397-1-12