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Synthesis and glycosidase inhibitory activity of new hexa-substituted C8-glycomimetics
BACKGROUND: Glycosidases are involved in several metabolic pathways and the development of inhibitors is an important challenge towards the treatment of diseases, such as diabetes, cancer and viral infections including AIDS. Thus, inhibition of intestinal α-glucosidases can be used to treat diabetes...
Autores principales: | Andriuzzi, Olivia, Gravier-Pelletier, Christine, Bertho, Gildas, Prangé, Thierry, Le Merrer, Yves |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1399460/ https://www.ncbi.nlm.nih.gov/pubmed/16542023 http://dx.doi.org/10.1186/1860-5397-1-12 |
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