Anti-HIV-1 activity of anionic polymers: a comparative study of candidate microbicides

BACKGROUND: Cellulose acetate phthalate (CAP) in soluble form blocks coreceptor binding sites on the virus envelope glycoprotein gp120 and elicits gp41 six-helix bundle formation, processes involved in virus inactivation. CAP is not soluble at pH < 5.5, normal for microbicide target sites. Theref...

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Detalles Bibliográficos
Autores principales: Neurath, A Robert, Strick, Nathan, Li, Yun-Yao
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139971/
https://www.ncbi.nlm.nih.gov/pubmed/12445331
http://dx.doi.org/10.1186/1471-2334-2-27

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139971/
https://www.ncbi.nlm.nih.gov/pubmed/12445331
http://dx.doi.org/10.1186/1471-2334-2-27

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