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Anti-HIV-1 activity of anionic polymers: a comparative study of candidate microbicides
BACKGROUND: Cellulose acetate phthalate (CAP) in soluble form blocks coreceptor binding sites on the virus envelope glycoprotein gp120 and elicits gp41 six-helix bundle formation, processes involved in virus inactivation. CAP is not soluble at pH < 5.5, normal for microbicide target sites. Theref...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2002
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139971/ https://www.ncbi.nlm.nih.gov/pubmed/12445331 http://dx.doi.org/10.1186/1471-2334-2-27 |