Infection of cells expressing CXCR4 mutants lacking N-glycosylation at the N-terminal extracellular domain is enhanced for R5X4-dualtropic human immunodeficiency virus type-1

BACKGROUND: Infection with human immunodeficiency virus type-1 (HIV-1) requires binding of the viral envelope gp120 to CD4 and to the CXCR4 coreceptor. Both, gp120 and CXCR4 are subject to N-glycosylation. Here we investigated the influence of the N-linked glycans g1 and g2 present on CXCR4 for HIV-...

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Detalles Bibliográficos
Autores principales: Thordsen, Ingo, Polzer, Svenja, Schreiber, Michael
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139973/
https://www.ncbi.nlm.nih.gov/pubmed/12489987
http://dx.doi.org/10.1186/1471-2334-2-31

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139973/
https://www.ncbi.nlm.nih.gov/pubmed/12489987
http://dx.doi.org/10.1186/1471-2334-2-31

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