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The differentiation status of primary gonadal germ cell tumors correlates inversely with telomerase activity and the expression level of the gene encoding the catalytic subunit of telomerase

BACKGROUND: The activity of the ribonucleoprotein enzyme telomerase is detectable in germ, stem and tumor cells. One major component of telomerase is human telomerase reverse transcriptase (hTERT), which encodes the catalytic subunit of telomerase. Here we investigate the correlation of telomerase a...

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Detalles Bibliográficos
Autores principales: Schrader, Mark, Burger, Angelika M, Müller, Markus, Krause, Hans, Straub, Bernd, Schostak, Martin, Schulze, Wolfgang, Lauke, Heidrun, Miller, Kurt
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139987/
https://www.ncbi.nlm.nih.gov/pubmed/12459049
http://dx.doi.org/10.1186/1471-2407-2-32