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Tracing Myelin Protein Zero (P0) in vivo by construction of P0-GFP fusion proteins

BACKGROUND: Mutations in P0, the major protein of the myelin sheath in peripheral nerves, cause the inherited peripheral neuropathies Charcot-Marie-Tooth disease type 1B (CMT1B), Dejerine-Sottas syndrome (DSS) and congenital hypomyelination (CH). We reported earlier a de novo insertional mutation c....

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Detalles Bibliográficos
Autores principales: Ekici, Arif B, Oezbey, Sevinc, Fuchs, Christina, Nelis, Eva, Van Broeckhoven, Christine, Schachner, Melitta, Rautenstrauss, Bernd
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139994/
https://www.ncbi.nlm.nih.gov/pubmed/12450416
http://dx.doi.org/10.1186/1471-2121-3-29