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Group I aptazymes as genetic regulatory switches

BACKGROUND: Allosteric ribozymes (aptazymes) that have extraordinary activation parameters have been generated in vitro by design and selection. For example, hammerhead and ligase ribozymes that are activated by small organic effectors and protein effectors have been selected from random sequence po...

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Detalles Bibliográficos
Autores principales: Thompson, Kristin M, Syrett, Heather A, Knudsen, Scott M, Ellington, Andrew D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139998/
https://www.ncbi.nlm.nih.gov/pubmed/12466025
http://dx.doi.org/10.1186/1472-6750-2-21