Cargando…

Outliers involving the Poly(A) effect among highly-expressed genes in microarrays

BACKGROUND: The Poly(A) effect is a cross-hybridization artifact in which poly(T)-containing molecules, which are produced by the reverse transcription of a poly(A)(+ )RNA mixture, bind promiscuously to the poly(A) stretches of the DNA in microarray spots. It is customary to attempt to block such hy...

Descripción completa

Detalles Bibliográficos
Autores principales: Pan, Shujia J, Rigney, David R, Ivy, John L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC140022/
https://www.ncbi.nlm.nih.gov/pubmed/12479797
http://dx.doi.org/10.1186/1471-2164-3-35