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Outliers involving the Poly(A) effect among highly-expressed genes in microarrays
BACKGROUND: The Poly(A) effect is a cross-hybridization artifact in which poly(T)-containing molecules, which are produced by the reverse transcription of a poly(A)(+ )RNA mixture, bind promiscuously to the poly(A) stretches of the DNA in microarray spots. It is customary to attempt to block such hy...
Autores principales: | Pan, Shujia J, Rigney, David R, Ivy, John L |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC140022/ https://www.ncbi.nlm.nih.gov/pubmed/12479797 http://dx.doi.org/10.1186/1471-2164-3-35 |
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