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The Metabolic Inhibition Model Which Predicts the Intestinal Absorbability and Metabolizability of Drug: Theory and Experiment
The intestinal absorption of analgesic peptides (leucine enkephalin and kyotorphin) and modified peptides in rat were studied. Although these peptides were not absorbed, the absorbability (absorption clearance) of these peptides were increased in the presence of peptidase inhibitors. In order to kin...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Biological Procedures Online
1998
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC140124/ https://www.ncbi.nlm.nih.gov/pubmed/12734588 http://dx.doi.org/10.1251/bpo8 |