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Xenoantigen, an αGal epitope-expression construct driven by the hTERT-promoter, specifically kills human pancreatic cancer cell line

BACKGROUND: We previously reported the usefulness of the αGal epitope as a target molecule for gene therapy against cancer. To induce cancer cell specific transcription of the αGal epitope, an expression vector which synthesizes the αGal epitope under the control of a promoter region of the human te...

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Detalles Bibliográficos
Autores principales: Sawada, Tokihiko, Yamada, Osamu, Yoshimura, Naoko, Hatori, Keiko, Fuchinoue, Shohei, Teraoka, Satoshi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC140132/
https://www.ncbi.nlm.nih.gov/pubmed/12392598
http://dx.doi.org/10.1186/1475-2867-2-14