BRCA1 Zinc RING Finger Domain Disruption Alters Caspase Response in Ovarian Surface Epithelial Cells

BACKGROUND: The frequently occurring 185delAG mutation occurs in the amino-terminal zinc RING domain of the breast and ovarian cancer susceptibility gene, BRCA1. We sought to determine differential cell viability and apoptotic response of human ovarian surface epithelial cells with and without the 1...

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Detalles Bibliográficos
Autores principales: Johnson, Nicole C, Kruk, Patricia A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC140135/
https://www.ncbi.nlm.nih.gov/pubmed/12234376
http://dx.doi.org/10.1186/1475-2867-2-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC140135/
https://www.ncbi.nlm.nih.gov/pubmed/12234376
http://dx.doi.org/10.1186/1475-2867-2-7

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