Flagellin-Deficient Legionella Mutants Evade Caspase-1- and Naip5-Mediated Macrophage Immunity

Macrophages from C57BL/6J (B6) mice restrict growth of the intracellular bacterial pathogen Legionella pneumophila. Restriction of bacterial growth requires caspase-1 and the leucine-rich repeat-containing protein Naip5 (Birc1e). We identified mutants of L. pneumophila that evade macrophage innate i...

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Detalles Bibliográficos
Autores principales: Ren, Tao, Zamboni, Dario S, Roy, Craig R, Dietrich, William F, Vance, Russell E
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1401497/
https://www.ncbi.nlm.nih.gov/pubmed/16552444
http://dx.doi.org/10.1371/journal.ppat.0020018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1401497/
https://www.ncbi.nlm.nih.gov/pubmed/16552444
http://dx.doi.org/10.1371/journal.ppat.0020018

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