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Flagellin-Deficient Legionella Mutants Evade Caspase-1- and Naip5-Mediated Macrophage Immunity
Macrophages from C57BL/6J (B6) mice restrict growth of the intracellular bacterial pathogen Legionella pneumophila. Restriction of bacterial growth requires caspase-1 and the leucine-rich repeat-containing protein Naip5 (Birc1e). We identified mutants of L. pneumophila that evade macrophage innate i...
Autores principales: | Ren, Tao, Zamboni, Dario S, Roy, Craig R, Dietrich, William F, Vance, Russell E |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1401497/ https://www.ncbi.nlm.nih.gov/pubmed/16552444 http://dx.doi.org/10.1371/journal.ppat.0020018 |
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