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Dual inhibitory effects of APOBEC family proteins on retrotransposition of mammalian endogenous retroviruses

We demonstrated previously that the cytosine deaminase APOBEC3G inhibits retrotransposition of two active murine endogenous retroviruses, namely intracisternal A-particles (IAP) and MusD, in an ex vivo assay where retrotransposition was monitored by selection of neo-marked elements. Sequencing of th...

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Detalles Bibliográficos
Autores principales: Esnault, Cécile, Millet, Jean, Schwartz, Olivier, Heidmann, Thierry
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1401513/
https://www.ncbi.nlm.nih.gov/pubmed/16537839
http://dx.doi.org/10.1093/nar/gkl054