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Development and application of a positive–negative selectable marker system for use in reverse genetics in Plasmodium

A limitation of transfection of malaria parasites is the availability of only a low number of positive selectable markers for selection of transformed mutants. This is exacerbated for the rodent parasite Plasmodium berghei as selection of mutants is performed in vivo in laboratory rodents. We here r...

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Detalles Bibliográficos
Autores principales: Braks, Joanna A. M., Franke-Fayard, Blandine, Kroeze, Hans, Janse, Chris J., Waters, Andrew P.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1401515/
https://www.ncbi.nlm.nih.gov/pubmed/16537837
http://dx.doi.org/10.1093/nar/gnj033