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The cell-specific activity of the estrogen receptor α may be fine-tuned by phosphorylation-induced structural gymnastics
The estrogen receptor α (ERα) regulates the transcription of target genes by recruiting coregulator proteins through several domains including the two activation functions AF1 and AF2. The contribution of the N-terminally located AF1 activity is particularly important in differentiated cells, and fo...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Nuclear Receptor Signaling Atlas
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1402211/ https://www.ncbi.nlm.nih.gov/pubmed/16604168 http://dx.doi.org/10.1621/nrs.04005 |