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Ligand-induced estrogen receptor α degradation by the proteasome: new actors?
In this perspective we consider new aspects of ligand-induced estrogen receptor α (ERα) degradation. What are the possible roles of CSN5/Jab1 and the CSN complex in this process? We compare hormone (estrogen) or pure antagonist (fulvestrant) induced degradation of ERα and review the effects of kinas...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Nuclear Receptor Signaling Atlas
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1402212/ https://www.ncbi.nlm.nih.gov/pubmed/16604167 http://dx.doi.org/10.1621/nrs.04004 |