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Ligand-induced estrogen receptor α degradation by the proteasome: new actors?

In this perspective we consider new aspects of ligand-induced estrogen receptor α (ERα) degradation. What are the possible roles of CSN5/Jab1 and the CSN complex in this process? We compare hormone (estrogen) or pure antagonist (fulvestrant) induced degradation of ERα and review the effects of kinas...

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Detalles Bibliográficos
Autores principales:	Calligé, Mathilde, Richard-Foy, Hélène
Formato:	Texto
Lenguaje:	English
Publicado:	The Nuclear Receptor Signaling Atlas 2006
Materias:	Perspective
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1402212/ https://www.ncbi.nlm.nih.gov/pubmed/16604167 http://dx.doi.org/10.1621/nrs.04004

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