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Linking lipids, Alzheimer's and LXRs?

Deposition of the β-amyloid (Aβ) peptide is thought to underlie development of Alzheimer's disease (AD). This pathological linkage has spurred considerable interest in therapeutic strategies to reduce Aβ production. It is becoming increasingly clear that altered cholesterol homeostasis can modu...

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Detalles Bibliográficos
Autores principales: Patel, Nilay V., Forman, Barry Marc
Formato: Texto
Lenguaje:English
Publicado: The Nuclear Receptor Signaling Atlas 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1402230/
https://www.ncbi.nlm.nih.gov/pubmed/16604185
http://dx.doi.org/10.1621/nrs.02001