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Linking lipids, Alzheimer's and LXRs?
Deposition of the β-amyloid (Aβ) peptide is thought to underlie development of Alzheimer's disease (AD). This pathological linkage has spurred considerable interest in therapeutic strategies to reduce Aβ production. It is becoming increasingly clear that altered cholesterol homeostasis can modu...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Nuclear Receptor Signaling Atlas
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1402230/ https://www.ncbi.nlm.nih.gov/pubmed/16604185 http://dx.doi.org/10.1621/nrs.02001 |