Evidence for conservation and selection of upstream open reading frames suggests probable encoding of bioactive peptides

BACKGROUND: Approximately 40% of mammalian mRNA sequences contain AUG trinucleotides upstream of the main coding sequence, with a quarter of these AUGs demarcating open reading frames of 20 or more codons. In order to investigate whether these open reading frames may encode functional peptides, we h...

Descripción completa

Detalles Bibliográficos
Autores principales: Crowe, Mark L, Wang, Xue-Qing, Rothnagel, Joseph A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1402274/
https://www.ncbi.nlm.nih.gov/pubmed/16438715
http://dx.doi.org/10.1186/1471-2164-7-16

Ejemplares similares

Ejemplares similares