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A novel expression system of domain I of human beta2 glycoprotein I in Escherichia coli

BACKGROUND: The antiphospholipid syndrome (APS), characterised by recurrent miscarriage and thrombosis, is a significant cause of morbidity and mortality. Domain I (DI) of human beta 2 glycoprotein I (β(2)GPI) is thought to contain crucial antibody binding epitopes for antiphospholipid antibodies (a...

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Detalles Bibliográficos
Autores principales: Ioannou, Yiannis, Giles, Ian, Lambrianides, Anastasia, Richardson, Chris, Pearl, Laurence H, Latchman, David S, Isenberg, David A, Rahman, Anisur
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1402286/
https://www.ncbi.nlm.nih.gov/pubmed/16472380
http://dx.doi.org/10.1186/1472-6750-6-8