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Increased therapeutic potential of an experimental anti-mitotic inhibitor SB715992 by genistein in PC-3 human prostate cancer cell line

BACKGROUND: Kinesin spindle proteins (KSP) are motor proteins that play an essential role in mitotic spindle formation. HsEg5, a KSP, is responsible for the formation of the bipolar spindle, which is critical for proper cell division during mitosis. The function of HsEg5 provides a novel target for...

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Detalles Bibliográficos
Autores principales: Davis, David A, Sarkar, Sarah H, Hussain, Maha, Li, Yiwei, Sarkar, Fazlul H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1402305/
https://www.ncbi.nlm.nih.gov/pubmed/16433906
http://dx.doi.org/10.1186/1471-2407-6-22