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Hypoxia-inducible transcription factor-1α promotes hypoxia-induced A549 apoptosis via a mechanism that involves the glycolysis pathway

BACKGROUND: Hypoxia-inducible transcription factor-1α (HIF-1α), which plays an important role in controlling the hypoxia-induced glycolysis pathway, is a "master" gene in the tissue hypoxia response during tumor development. However, its role in the apoptosis of non-small cell lung cancer...

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Detalles Bibliográficos
Autores principales: Luo, FengMing, Liu, XiaoJing, Yan, NaiHong, Li, ShuangQing, Cao, GuiQun, Cheng, QingYing, Xia, QingJie, Wang, HongJing
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1402310/
https://www.ncbi.nlm.nih.gov/pubmed/16438736
http://dx.doi.org/10.1186/1471-2407-6-26