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CARAT: A novel method for allelic detection of DNA copy number changes using high density oligonucleotide arrays

BACKGROUND: DNA copy number alterations are one of the main characteristics of the cancer cell karyotype and can contribute to the complex phenotype of these cells. These alterations can lead to gains in cellular oncogenes as well as losses in tumor suppressor genes and can span small intervals as w...

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Detalles Bibliográficos
Autores principales: Huang, Jing, Wei, Wen, Chen, Joyce, Zhang, Jane, Liu, Guoying, Di, Xiaojun, Mei, Rui, Ishikawa, Shumpei, Aburatani, Hiroyuki, Jones, Keith W, Shapero, Michael H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1402331/
https://www.ncbi.nlm.nih.gov/pubmed/16504045
http://dx.doi.org/10.1186/1471-2105-7-83