Cargando…

No simple dependence between protein evolution rate and the number of protein-protein interactions: only the most prolific interactors tend to evolve slowly

BACKGROUND: It has been suggested that rates of protein evolution are influenced, to a great extent, by the proportion of amino acid residues that are directly involved in protein function. In agreement with this hypothesis, recent work has shown a negative correlation between evolutionary rates and...

Descripción completa

Detalles Bibliográficos
Autores principales: Jordan, I King, Wolf, Yuri I, Koonin, Eugene V
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC140311/
https://www.ncbi.nlm.nih.gov/pubmed/12515583
http://dx.doi.org/10.1186/1471-2148-3-1