Strict control of telomerase activation using Cre-mediated inversion

BACKGROUND: Human cells appear exquisitely sensitive to the levels of hTERT expression, the telomerase reverse transcriptase. In primary cells that do not express hTERT, telomeres erode with each successive cell division, leading to the eventual loss of telomere DNA, an induction of a telomere DNA d...

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Detalles Bibliográficos
Autores principales: Ungrin, Mark D, Harrington, Lea
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1403769/
https://www.ncbi.nlm.nih.gov/pubmed/16504006
http://dx.doi.org/10.1186/1472-6750-6-10

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1403769/
https://www.ncbi.nlm.nih.gov/pubmed/16504006
http://dx.doi.org/10.1186/1472-6750-6-10

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