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Tissue distribution of a plasmid DNA encoding Hsp65 gene is dependent on the dose administered through intramuscular delivery

In order to assess a new strategy of DNA vaccine for a more complete understanding of its action in immune response, it is important to determine the in vivo biodistribution fate and antigen expression. In previous studies, our group focused on the prophylactic and therapeutic use of a plasmid DNA e...

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Detalles Bibliográficos
Autores principales: Coelho-Castelo, AAM, Trombone, AP, Rosada, RS, Santos, RR, Bonato, VLD, Sartori, A, Silva, CL
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1403771/
https://www.ncbi.nlm.nih.gov/pubmed/16445866
http://dx.doi.org/10.1186/1479-0556-4-1