Cargando…

Criteria for effective design, construction, and gene knockdown by shRNA vectors

BACKGROUND: RNA interference (RNAi) technology is a powerful methodology recently developed for the specific knockdown of targeted genes. RNAi is most commonly achieved either transiently by transfection of small interfering (si) RNA oligonucleotides, or stably using short hairpin (sh) RNA expressed...

Descripción completa

Detalles Bibliográficos
Autores principales: Taxman, Debra J, Livingstone, Laura R, Zhang, Jinghua, Conti, Brian J, Iocca, Heather A, Williams, Kristi L, Lich, John D, Ting, Jenny P-Y, Reed, William
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1409772/
https://www.ncbi.nlm.nih.gov/pubmed/16433925
http://dx.doi.org/10.1186/1472-6750-6-7