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A new pooling strategy for high-throughput screening: the Shifted Transversal Design
BACKGROUND: In binary high-throughput screening projects where the goal is the identification of low-frequency events, beyond the obvious issue of efficiency, false positives and false negatives are a major concern. Pooling constitutes a natural solution: it reduces the number of tests, while provid...
Autor principal: | Thierry-Mieg, Nicolas |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1409803/ https://www.ncbi.nlm.nih.gov/pubmed/16423300 http://dx.doi.org/10.1186/1471-2105-7-28 |
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