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CYP17 gene polymorphism in relation to breast cancer risk: a case-control study

INTRODUCTION: The c.1-34T>C 5' promoter region polymorphism in cytochrome P450c17 (CYP17), a key enzyme in the biosynthesis of estrogen, has been associated with breast cancer risk, but most previous studies have been relatively small. METHODS: We genotyped 1,544 incident cases of primary br...

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Detalles Bibliográficos
Autores principales: Einarsdóttir, Kristjana, Rylander-Rudqvist, Tove, Humphreys, Keith, Ahlberg, Susanne, Jonasdottir, Gudrun, Weiderpass, Elisabete, Chia, Kee Seng, Ingelman-Sundberg, Magnus, Persson, Ingemar, Liu, Jianjun, Hall, Per, Wedrén, Sara
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1410739/
https://www.ncbi.nlm.nih.gov/pubmed/16280037
http://dx.doi.org/10.1186/bcr1319