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Clioquinol and pyrrolidine dithiocarbamate complex with copper to form proteasome inhibitors and apoptosis inducers in human breast cancer cells

INTRODUCTION: A physiological feature of many tumor tissues and cells is the tendency to accumulate high concentrations of copper. While the precise role of copper in tumors is cryptic, copper, but not other trace metals, is required for angiogenesis. We have recently reported that organic copper-co...

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Detalles Bibliográficos
Autores principales: Daniel, Kenyon G, Chen, Di, Orlu, Shirley, Cui, Qiuzhi Cindy, Miller, Fred R, Dou, Q Ping
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1410741/
https://www.ncbi.nlm.nih.gov/pubmed/16280039
http://dx.doi.org/10.1186/bcr1322