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Effects of combined treatment with rapamycin and cotylenin A, a novel differentiation-inducing agent, on human breast carcinoma MCF-7 cells and xenografts

INTRODUCTION: Rapamycin, an inhibitor of the serine/threonine kinase target of rapamycin, induces G(1 )arrest and/or apoptosis. Although rapamycin and its analogues are attractive candidates for cancer therapy, their sensitivities with respect to growth inhibition differ markedly among various cance...

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Detalles Bibliográficos
Autores principales: Kasukabe, Takashi, Okabe-Kado, Junko, Kato, Nobuo, Sassa, Takeshi, Honma, Yoshio
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1410757/
https://www.ncbi.nlm.nih.gov/pubmed/16457690
http://dx.doi.org/10.1186/bcr1344