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Rac1 and Rac3 isoform activation is involved in the invasive and metastatic phenotype of human breast cancer cells
INTRODUCTION: The metastatic progression of cancer is a direct result of the disregulation of numerous cellular signaling pathways, including those associated with adhesion, migration, and invasion. Members of the Rac family of small GTPases are known to act as regulators of actin cytoskeletal struc...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1410764/ https://www.ncbi.nlm.nih.gov/pubmed/16280046 http://dx.doi.org/10.1186/bcr1329 |