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Rac1 and Rac3 isoform activation is involved in the invasive and metastatic phenotype of human breast cancer cells

INTRODUCTION: The metastatic progression of cancer is a direct result of the disregulation of numerous cellular signaling pathways, including those associated with adhesion, migration, and invasion. Members of the Rac family of small GTPases are known to act as regulators of actin cytoskeletal struc...

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Detalles Bibliográficos
Autores principales: Baugher, Paige J, Krishnamoorthy, Lakshmi, Price, Janet E, Dharmawardhane, Surangani F
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1410764/
https://www.ncbi.nlm.nih.gov/pubmed/16280046
http://dx.doi.org/10.1186/bcr1329