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Regions of extreme synonymous codon selection in mammalian genes

Recently there has been increasing evidence that purifying selection occurs among synonymous codons in mammalian genes. This selection appears to be a consequence of either cis-regulatory motifs, such as exonic splicing enhancers (ESEs), or mRNA secondary structures, being superimposed on the coding...

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Detalles Bibliográficos
Autores principales: Schattner, Peter, Diekhans, Mark
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1410912/
https://www.ncbi.nlm.nih.gov/pubmed/16556911
http://dx.doi.org/10.1093/nar/gkl095