Studies of Caenorhabditis elegans DAF-2/insulin signaling reveal targets for pharmacological manipulation of lifespan

Much excitement has arisen from the observation that decrements in insulin-like signaling can dramatically extend lifespan in the nematode, Caenorhabditis elegans, and fruitfly, Drosophila melanogaster. In addition, there are tantalizing hints that the IGF-I pathway in mice may have similar effects....

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Detalles Bibliográficos
Autores principales: Gami, Minaxi S, Wolkow, Catherine A
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2006
Materias:
Special Issue
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1413578/
https://www.ncbi.nlm.nih.gov/pubmed/16441841
http://dx.doi.org/10.1111/j.1474-9726.2006.00188.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1413578/
https://www.ncbi.nlm.nih.gov/pubmed/16441841
http://dx.doi.org/10.1111/j.1474-9726.2006.00188.x

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