New role for nuclear hormone receptors and coactivators in regulation of BRCA1-mediated DNA repair in breast cancer cell lines

INTRODUCTION: The breast cancer susceptibility gene BRCA1 is involved in the repair of double-strand breaks induced by ionizing radiation and chemotherapy drugs. BRCA1 interacts with coactivators such as p300 and CREB-binding protein (CBP) to activate target gene transcription. Estrogen and retinoic...

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Detalles Bibliográficos
Autores principales: Crowe, David L, Lee, Matt K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1413977/
https://www.ncbi.nlm.nih.gov/pubmed/16417649
http://dx.doi.org/10.1186/bcr1362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1413977/
https://www.ncbi.nlm.nih.gov/pubmed/16417649
http://dx.doi.org/10.1186/bcr1362

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