BRCA1 and BRCA2 mutation predictions using the BOADICEA and BRCAPRO models and penetrance estimation in high-risk French-Canadian families

INTRODUCTION: Several genetic risk models for breast and ovarian cancer have been developed, but their applicability to specific populations has not been evaluated. We used data from French-Canadian families to evaluate the mutation predictions given by the BRCAPRO and BOADICEA models. We also used...

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Detalles Bibliográficos
Autores principales: Antoniou, Antonis C, Durocher, Francine, Smith, Paula, Simard, Jacques, Easton, Douglas F
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1413985/
https://www.ncbi.nlm.nih.gov/pubmed/16417652
http://dx.doi.org/10.1186/bcr1365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1413985/
https://www.ncbi.nlm.nih.gov/pubmed/16417652
http://dx.doi.org/10.1186/bcr1365

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