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Compound developmental eye disorders following inactivation of TGFβ signaling in neural-crest stem cells

BACKGROUND: Development of the eye depends partly on the periocular mesenchyme derived from the neural crest (NC), but the fate of NC cells in mammalian eye development and the signals coordinating the formation of ocular structures are poorly understood. RESULTS: Here we reveal distinct NC contribu...

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Detalles Bibliográficos
Autores principales: Ittner, Lars M, Wurdak, Heiko, Schwerdtfeger, Kerstin, Kunz, Thomas, Ille, Fabian, Leveen, Per, Hjalt, Tord A, Suter, Ueli, Karlsson, Stefan, Hafezi, Farhad, Born, Walter, Sommer, Lukas
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1414066/
https://www.ncbi.nlm.nih.gov/pubmed/16403239
http://dx.doi.org/10.1186/jbiol29