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Analysis of polymorphisms in 16 genes in type 1 diabetes that have been associated with other immune-mediated diseases
BACKGROUND: The identification of the HLA class II, insulin (INS), CTLA-4 and PTPN22 genes as determinants of type 1 diabetes (T1D) susceptibility indicates that fine tuning of the immune system is centrally involved in disease development. Some genes have been shown to affect several immune-mediate...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1420277/ https://www.ncbi.nlm.nih.gov/pubmed/16519819 http://dx.doi.org/10.1186/1471-2350-7-20 |