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Analysis of polymorphisms in 16 genes in type 1 diabetes that have been associated with other immune-mediated diseases

BACKGROUND: The identification of the HLA class II, insulin (INS), CTLA-4 and PTPN22 genes as determinants of type 1 diabetes (T1D) susceptibility indicates that fine tuning of the immune system is centrally involved in disease development. Some genes have been shown to affect several immune-mediate...

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Detalles Bibliográficos
Autores principales: Smyth, Deborah J, Howson, Joanna MM, Payne, Felicity, Maier, Lisa M, Bailey, Rebecca, Holland, Kieran, Lowe, Christopher E, Cooper, Jason D, Hulme, John S, Vella, Adrian, Dahlman, Ingrid, Lam, Alex C, Nutland, Sarah, Walker, Neil M, Twells, Rebecca CJ, Todd, John A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1420277/
https://www.ncbi.nlm.nih.gov/pubmed/16519819
http://dx.doi.org/10.1186/1471-2350-7-20