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Analysis of polymorphisms in 16 genes in type 1 diabetes that have been associated with other immune-mediated diseases
BACKGROUND: The identification of the HLA class II, insulin (INS), CTLA-4 and PTPN22 genes as determinants of type 1 diabetes (T1D) susceptibility indicates that fine tuning of the immune system is centrally involved in disease development. Some genes have been shown to affect several immune-mediate...
Autores principales: | Smyth, Deborah J, Howson, Joanna MM, Payne, Felicity, Maier, Lisa M, Bailey, Rebecca, Holland, Kieran, Lowe, Christopher E, Cooper, Jason D, Hulme, John S, Vella, Adrian, Dahlman, Ingrid, Lam, Alex C, Nutland, Sarah, Walker, Neil M, Twells, Rebecca CJ, Todd, John A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1420277/ https://www.ncbi.nlm.nih.gov/pubmed/16519819 http://dx.doi.org/10.1186/1471-2350-7-20 |
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