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The protein kinase DYRK1A phosphorylates the splicing factor SF3b1/SAP155 at Thr434, a novel in vivo phosphorylation site

BACKGROUND: The U2 small nuclear ribonucleoprotein particle (snRNP) component SF3b1/SAP155 is the only spliceosomal protein known to be phosphorylated concomitant with splicing catalysis. DYRK1A is a nuclear protein kinase that has been localized to the splicing factor compartment. Here we describe...

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Detalles Bibliográficos
Autores principales: de Graaf, Katrin, Czajkowska, Hanna, Rottmann, Sabine, Packman, Len C, Lilischkis, Richard, Lüscher, Bernhard, Becker, Walter
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1420302/
https://www.ncbi.nlm.nih.gov/pubmed/16512921
http://dx.doi.org/10.1186/1471-2091-7-7