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Genetic variation in the myeloperoxidase gene and cognitive impairment in Multiple Sclerosis

There is evidence that multiple sclerosis (MS) may associated with cognitive impairment in 25 to 40% of cases. The gene encoding myeloperoxidase (MPO) is involved in molecular pathways leading to β-amyloid deposition. We investigated a functional biallelic (G/A) polymorphism in the promoter region (...

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Detalles Bibliográficos
Autores principales: Manna, I, Valentino, P, La Russa, A, Condino, F, Nisticò, R, Liguori, M, Clodomiro, A, Andreoli, V, Pirritano, D, Cittadella, R, Quattrone, A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1420327/
https://www.ncbi.nlm.nih.gov/pubmed/16504169
http://dx.doi.org/10.1186/1477-5751-5-3