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Genetic variation in the myeloperoxidase gene and cognitive impairment in Multiple Sclerosis
There is evidence that multiple sclerosis (MS) may associated with cognitive impairment in 25 to 40% of cases. The gene encoding myeloperoxidase (MPO) is involved in molecular pathways leading to β-amyloid deposition. We investigated a functional biallelic (G/A) polymorphism in the promoter region (...
Autores principales: | Manna, I, Valentino, P, La Russa, A, Condino, F, Nisticò, R, Liguori, M, Clodomiro, A, Andreoli, V, Pirritano, D, Cittadella, R, Quattrone, A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1420327/ https://www.ncbi.nlm.nih.gov/pubmed/16504169 http://dx.doi.org/10.1186/1477-5751-5-3 |
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