Adduct-specific monoclonal antibodies for the measurement of cisplatin-induced DNA lesions in individual cell nuclei

The anticancer drug cisplatin executes its cytotoxic activity via formation of intra- and interstrand crosslinks in DNA. The relative contribution of structurally defined cisplatin adducts to induce apoptosis and the cellular processing of these lesions is still poorly understood mostly due to the l...

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Detalles Bibliográficos
Autores principales: Liedert, Bernd, Pluim, Dick, Schellens, Jan, Thomale, Jürgen
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1420801/
https://www.ncbi.nlm.nih.gov/pubmed/16571898
http://dx.doi.org/10.1093/nar/gkl051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1420801/
https://www.ncbi.nlm.nih.gov/pubmed/16571898
http://dx.doi.org/10.1093/nar/gkl051

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