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The fibrinolytic system facilitates tumor cell migration across the blood-brain barrier in experimental melanoma brain metastasis

BACKGROUND: Patients with metastatic tumors to the brain have a very poor prognosis. Increased metastatic potential has been associated with the fibrinolytic system. We investigated the role of the fibrinolytic enzyme plasmin in tumor cell migration across brain endothelial cells and growth of brain...

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Detalles Bibliográficos
Autores principales: Perides, George, Zhuge, Yuzheng, Lin, Tina, Stins, Monique F, Bronson, Roderick T, Wu, Julian K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1421425/
https://www.ncbi.nlm.nih.gov/pubmed/16524486
http://dx.doi.org/10.1186/1471-2407-6-56