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The fibrinolytic system facilitates tumor cell migration across the blood-brain barrier in experimental melanoma brain metastasis
BACKGROUND: Patients with metastatic tumors to the brain have a very poor prognosis. Increased metastatic potential has been associated with the fibrinolytic system. We investigated the role of the fibrinolytic enzyme plasmin in tumor cell migration across brain endothelial cells and growth of brain...
Autores principales: | Perides, George, Zhuge, Yuzheng, Lin, Tina, Stins, Monique F, Bronson, Roderick T, Wu, Julian K |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1421425/ https://www.ncbi.nlm.nih.gov/pubmed/16524486 http://dx.doi.org/10.1186/1471-2407-6-56 |
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